Bing Zhou, PhD, graduated from Fudan University, Shanghai, China (1987), and obtained his PhD degree from University of California at Berkeley (1995). After postdoctoral training at University of California at San Francisco, he served as a principle investigator at Tsinghua University before joining in SIAT. Primary interests of the lab are in two areas: 1) trace element(Fe/Zn) metabolism and relevant diseases; 2) the antimalarial action of Qinghaosu(artemisinin). Facilitated by molecular, cellular and genetic approaches, the group combines the use of various model organisms such as yeast, the fruit fly as well as mouse to tackle these problems.
EMAIL: bing.zhou@siat.ac.cn
Publications/Patents(seleceted)
Yin S, Qin Q, Zhou B (2017). Functional studies of Drosophila zinc transporters reveal the mechanism for zinc excretion in Malpighian tubules. BMC Biol. 2017 Feb 14; 15(1):12. doi: 10.1186/s12915-017-0355-9.
Xiao G, Wan Z, Fan Q, Tang X, Zhou B (2014). The metal transporter ZIP13 supplies iron into the secretory pathway in Drosophila melanogaster. Elife 3:e03191. doi: 10.7554/eLife.03191.
Huang Y, Wu Z, Cao Y, Lang M, Lu B, Zhou B (2014). Direct Zinc Binding Is Critical for Tau Toxicity Independent of Hyperphosphorylation. Cell Reports 8(3):831-42.
Xiao G, Fan Q, Wang X, Zhou B (2013). Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding. Proc Natl Acad Sci U S A 110 (37):14995-5000.
Qin Q, Wang X, Zhou B (2013). Functional studies of Drosophila zinc transporters reveal the mechanism for dietary zincabsorption and regulation. BMC Biol. 11:101. doi: 10.1186/1741-7007-11-101.