Using cutting-edge technologies of synthetic biology, the emerging field of Synthetic Microbiome aims to engineer complex microbial communities to achieve desired function and stability. Rational design and precise modulation of microbial communities holds promise for solving important issues in multiple areas, including human health, sustainable agriculture, etc. The Center for Synthetic Microbiome will create an innovative ecosystem to promote basic research of synthetic microbial communities as well as their applications in medicine, agriculture and bio-manufacturing.
He is particularly interested in systematic and integrative analysis of pan-genomes of microbial taxa with the information of related metagenomes of microbiomes.
Focos on developing quantitative models and synthetic biology tools to engineer microbial communities that play important roles in human health, agriculture and environment.
Our studies are supported by various grants more than ten million Yuan from Shenzhen government and Chinese National Science Foundation.
Using system biology and synthetic biology approaches, we investigate the mechanisms underlying the antifungal resistance and the pathogenesis of the human-associated fungi. We also study the interactions between the fungal and bacterial compartments of human microbiome, and their influence on different physiological and disease processes
Dr. Ho Chun Loong’s research focuses primarily on using synthetic biology and protein engineering to address various health and environmental issues. This includes establishing a platform where researchers could share their constructs and systematically amass these genetic constructs for protein engineering purposes.