Focusing on key scientific questions about microbial evolution and interacting mechanisms between microbes and corresponding environment, the Center for Quantitative Synthetic Biology (CQSB) has deployed two main research directions, which are theoretical foundation and enabling technology, and conducted extensive explorations in practical applications as well. In order to exploit the combination of quantitative technology and synthetic biology, the center has attracted multidisciplinary and complementary groups from synthetic biology, microbiology, physics, bioinformatics, microfluidics, and proteomics and so on, with more than ten outstanding young Principal Investigators and about 200 researchers.
The research interest in his lab currently focuses on bacterial cancer therapy, bacterial cell cycle, and directed evolution.
Focusing on the application of quantitative analytics and advanced instrumentation from physics and engineering to biological study, to facilitate our design ability of living system.
Integrating approaches in genomics, computational biology and evolutionary biology to understand the clonal evolution in somatic tissue and cancer.
Research on synthetic biology methodology based on micro-nanometer and high-throughput detection and analysis technology
The current research interest of Prof. Jin is primarily in the area of methodology of quantitative and evolutionary biology.
The research focus of Dr. Chen’s lab is to understand and further program the fate of stem cells. Driven by this primary interest, they actively develop and utilize multidisciplinary technologies to address the methodologically inaccessible questions.
Development of new strategies and systems for studying virus infection, prevention, and control.
He is interested in integrating synthetic biology, robotic automation, and high-throughput analytical approaches to address grant challenges in human health and sustainablity via fundamental and applied research on biocatalysis and biosynthesis.
The role of chemical proteomics in synthetic biology and molecular pharmacology
Dr. Li is interested in understanding the mechanisms underlying bacterial-based tumor therapies and the immune exclusion in cancer, by combining computational modeling and quantitative data analysis.
Investigate the roles of intracellular transportation in development, cellular function and diseases; Use synthetic biology approach to investigate biological pattern/structure formation, to develop vaccines against infectious diseases, and to create novel cancer treatment
The current research interests include biosensors, nano-biology and molecular/cellular imaging and their applications in virology and cancer biology.
Translate Microbial Natural Products into drugs for life-threatening diseases.
Focused on finding genes, cancer stem cells and tumor microenvironment associated with HCC, esophageal cancer and nasopharyngeal carcinoma.
Genetics, genomics, bioinformatics
Dr. Hu is majoring in the research on genetic research of human diseases related and tumor immunotherapy.
DNA Damage Detection and Repair Control
Analytical and computational approaches to explore the effect of equilibrium and nonequilibrium fluctuations on the stability of ordered structures in various physical and biophysical contexts; collective behavior and pattern formation in biological systems
Research and development of biological experimental equipment, precision engineering.
His current research interests include directed evolution of membrane proteins, applied microbiology, and policy and ethics study of synthetic biology.
Wnt regulation of planar cell polarity in development and disease
Genomics, Bioinformatics, Computational Biology, Sequencing technologies, Cancer Diagnostics, Microfluids based Diagnostics
Emergence of life, Tumor evolution, R&D of anti-tumor drugs
Gene regulation