The Center for Synthetic Biochemistry (CSB) is built from cross disciplinary research groups that bring together many outstanding young talents in the fields of microbiology, synthetic biology, materials chemistry, metabolic engineering and analytical chemistry. The center is committed to the development of theories and methodologies useful for the creation of new synthetic biochemical pathways that can meet the needs of market demands and regional strategies. CSB is also engaged in building a cutting-edge synthetic biology technology platform to rapidly engineer the metabolic pathways that already exists in nature (found in fungi, plants, and animals) in synthetic microorganisms that are able to transform cheap raw materials into valuable natural or non-natural products.
In the basis of big data machine learning and high-throughput automation approaches, explore the biosynthesis approaches of diverse natural products and their derivatives based on big data machine learning and high-throughput automation by combining various biochemical methods of genetic code expansion, directed evolution of enzymes, gene mining and metabolic engineering.
Natural product biosynthesis, structural enzymology, enzyme design
Synthetic metabolism or Metabolic rewiring, Evolution engineering and Metabolic engineering.
Focuses on developing the next generation of biological catalysts that can help meet the ever-growing need for new medicines and new materials, and the next generation of sustainable industrial processes using biology.
The Jiang Lab seeks to elucidate the biosynthetic pathways and biological roles of natural products related to human health and diseases.
Organismic Interactions, Big Data Analysis, multi-omics Technologies, Chemical languages, Drug lead Discovery.
Yu CHEN