司龙龙博士/研究员

病毒感染及防治研究的新策略和新系统。

司龙龙博士,中科院深圳先进技术研究院合成生物学研究所研究员。于四川大学华西药学院获得药学学士学位,于北京大学药学院/天然药物及仿生药物国家重点实验室获得化学生物学博士学位,在哈佛大学Wyss研究所、哈佛医学院作为博士后、Wyss技术研发研究员从事生物医学工程、合成生物学研究。近年来研究成果发表在Science, Nature Biomedical Engineering, Science Advances, Biomaterials等期刊。

 

联系邮箱:ll.si@siat.ac.cn

个人网站:http://isynbio.siat.ac.cn/SLlab/


发表文章节选


Si L#, Bai H#, Rodas M, Cao W, Oh CY, Jiang A, Moller R, Hoagland D, Oishi K, Horiuchi S, Uhl S, Blanco-Melo D, Albrecht RA, Liu WC, Jordan T, Nilsson-Payant BE, Golynker I, Frere J, Logue J, Haupt R, McGrath M, Weston S, Zhang T, Plebani R, Soong M, Nurani A, Kim SM, Zhu DY, Benam KH, Goyal G, Gilpin SE, Prantil-Baun R, Gygi SP, Powers RK, Carlson KE, Frieman M, tenOever BR, Ingber DE*. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nature Biomedical Engineering 2021. https://doi.org/10.1038/s41551-021-00718-9 (#co-first author, *corresponding author)

Si L#, Bai H#, Oh CY, Jin L, Prantial-Baun R, Ingber DE*. Clinically relevant influenza virus evolution reconstituted in a human lung airway-on-a-chip. Microbiology Spectrum 2021. (#co-first author, *corresponding author)

Si L, Meng K, Tian Z, Sun J, Li H, Zhang Z, Soloveva V, Li H, Fu G, Xia Q, Xiao S, Zhang L, Zhou D*. Triterpenoids manipulate a broad range of virus-host fusion via wrapping the HR2 domain prevalent in viral envelopes. Science Advances 2018; 4: eaau8408.

Si L#, Xu H#, Zhou X, Zhang Z, Tian Z, Wang Y, Wu Y, Zhang B, Niu Z, Zhang C, Fu G, Xiao S, Xia Q, Zhang L, Zhou D*. Generation of influenza A viruses as live but replication-incompetent virus vaccines. Science 2016; 354: 1170-1173. (#co-first author, *corresponding author)

Xiao S#*, Si L#, Tian Z, Jiao P, Fan Z, Meng K, Zhou X, Wang H, Xu R, Han X, Fu G, Zhang Y, Zhang L, Zhou D*. Pentacyclic triterpenes grafted on CD cores to interfere with influenza virus entry: A dramatic multivalent effect. Biomaterials 2016; 78: 74-85. (#co-first author, *corresponding author)