陈万泽博士/研究员

通过对新技术尤其是单细胞分析技术的开发和利用,探索调节干细胞命运的程序,进而尝试运用合成生物学手段对细胞命运进行主动改造。

陈万泽博士,中科院深圳先进技术研究院合成生物学研究所研究员。他博士毕业于厦门大学,师从韩家淮院士。在瑞士洛桑联邦理工学院遗传学和系统生物学实验室从事博士后研究,期间获欧盟玛丽居里奖学金。以(共同)第一作者在Nature Cell Biology, Cell Research, Nature Communication, JBC等学术期刊上发表多篇研究论文。

 

联系邮箱:wz.chen@siat.ac.cn

链接:http://isynbio.siat.ac.cn/view.php?id=553


发表文章节选

Chen, W. #, Guillaume-Gentil, O. #, Dainese, R., Rainer, P., Zachara, M., Gäbelein, C., Vorholt, J., Deplancke, B. Live cell transcriptome profiling using Live-seq. (bioRxiv, 2021)

Chen W#, Schwalie PC#, et al., ZFP30 promotes adipogenesis through the KAP1-mediated activation of a retrotransposon-derived Pparg2 enhancer. Nature Communications (2019)

Chen W, Gardeux V, et al., Profiling of Single-Cell Transcriptomes. Current Protocols in Mouse Biology (2017)

Chen W, Wu J, et al., Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nature Cell Biology (2015)

Li L#, Chen W#, Liang Y#, et al., Gβγ-Src signaling pathway via control of the translocation of necrosome regulates TNF-induced necroptosis. Cell Research (2014)

Chen W#, Zhou Z#, Li L#, et al., Diverse Sequence Determinants Control Human and Mouse Receptor Interacting Protein 3 (RIP3) and Mixed Lineage Kinase domain-Like (MLKL) Interaction in Necroptotic Signaling. J Biol Chem (2013)