资治科博士/研究员

系统生物学

资治科,研究员,国家重大人才工程(青年)专家。课题组主要研究方向为细胞信号转导系统的调控原理与合成控制、细胞系统的数学建模和机器学习预测。目前在相关领域发表了25篇论文,以通讯作者发表在Molecular Systems Biology、Bioinformatics、ACS Synthetic Biology、iScience等期刊上。其他参与的工作发表在 Nature Methods、Developmental Cell、Science Signaling、Autophagy等杂志上。

联系邮箱:zk.zi@siat.ac.cn

实验室主页: zilab.org


论文发表节选:

van Jaarsveld MTM, Deng D, Ordoñez-Rueda D, Paulsen M, Wiemer EAC, Zi Z. Cell-type-specific role of CHK2 in mediating DNA damage-induced G2 cell cycle arrest. Oncogenesis, 2020, 9:35

Han H, Wu G, Li Y, Zi Z. eDetect: A Fast Error Detection and Correction Tool for Live Cell Imaging Data Analysis. iScience, 2019, 13:1-8.

Li Y, Lee M, Kim N, Wu G, Deng D, Kim JM, Liu X, Heo WD, Zi Z. Spatiotemporal Control of TGF-β Signaling with Light. ACS Synthetic Biology, 2018, 7:443-451.

Zi Z*, Feng Z, Chapnick DA, Dahl M, Deng D, Klipp E, Moustakas A, Liu X*. Quantitative analysis of transient and sustained transforming growth factor-β signaling dynamics. Molecular Systems Biology. 2011, 7:492. (* Corresponding authors)

Adrover MÀ#, Zi Z#, Duch A, Schaber J, González-Novo A, Jimenez J, Nadal-Ribelles M, Clotet J, Klipp E, Posas F. Time-dependent quantitative multicomponent control of the G₁-S network by the stress-activated protein kinase Hog1 upon osmostress. Science Signaling, 2011, 4:ra63. (# co-first authors)