戴磊博士/中心主任

合成微生物组的设计和调控

戴磊博士,中国科学院深圳先进技术研究院研究员、博士生导师,深圳合成生物学创新研究院微生物组研究中心主任。国家重点研发计划青年项目首席科学家,入选《麻省理工科技评论》中国区“35岁以下科技创新35人”。实验室利用合成生物学的工具,对微生物组的结构和功能进行理性设计和精准调控,致力于解决人体健康、农业生产等重大问题。研究成果以第一作者或通讯作者发表在Science、Nature、PNAS、eLife等国际学术期刊。

联系方式:0755-86392436

联系邮箱:lei.dai@siat.ac.cn

个人主页:http://isynbio.siat.ac.cn/leidailab


论文发表节选

Du, Y., Xin, L., Shi, Y., Zhang, T., Wu, N.C., Dai, L., Gong, D., Brar, G.,Shu,S., Luo, J., Reiley, W., Tseng, Y., Bai, H., Wu, T., Wang, J., Shu, Y., Sun, R. Genome-wide identification of interferon-sensitive mutations enables influenza vaccine design. Science (2018)

Du, Y.*, Zhang, T.*, Dai, L.*, Zheng, X.*, Gorin, A., Oishi, J., Wu, T., Yoshizawa J.M., Li, X., Yang O.O.,Martinez, O., Detels, R., Sun, R. 1. Effects of mutations on replicative fitness and MHC-I binding affinity are among the determinants underlying CTL escape of HIV-1 Gag Epitopes. mBio (2017)

Rindi, L., Dal Bello M., Dai, L., Gore J., Benedetti-Cecchi L. Direct observation of increasing recovery length before collapse of a marine benthic ecosystem. Nature Ecology & Evolution (2017)

Wu, N.C.*, Dai, L.*, Olson, C.A., Lloyd-Smith, J.O., Sun, R. Adaptation in protein fitness landscapes is facilitated by indirect paths. eLife (2016)

Dai, L., Korolev, K.S., Gore, J. Relation between stability and resilience determines the performance of early warning signals under different environmental drivers. PNAS (2015)