于涛博士/研究员

细胞工厂构建及其代谢原理解析

于涛博士,中科院深圳先进技术研究院合成生物学研究所研究员,他于山东大学获得生物技术学士学位,于中科院上海生物化学与细胞生物学研究所硕博连读获得生物化学与分子生物学博士学位,在瑞典Chalmers理工大学从事博士后研究。近五年来研究成果发表在Cell, Cell Research, Nat Communications等国际知名期刊。

联系邮箱:tao.yu@siat.ac.cn

个人网站:http://isynbio.siat.ac.cn/yutaolab/


论文发表节选

Yu T*, Dabirian Y*, Liu Q, Siewers V, Nielsen J. Challenges and Strategies for Metabolic Rewiring. Current Opinion in Systems Biology. 2019. (*co-first author)

Yu T*, Zhou Y .J.J*, Huang M, Liu Q, Pereira R, David F, Nielsen J. Reprogramming Yeast Metabolism from Alcoholic Fermentation to Lipogenesis. Cell 2018, 174:1549-1558 e1514. (*co-first author)

Yu, T., Zhou, Y.J.J., Wenning, L., Liu, Q.L., Krivoruchko, A., Siewers, V., Nielsen, J., and David, F. (2017). Metabolic engineering of Saccharomyces cerevisiae for production of very long chain fatty acid-derived chemicals. Nature Communications 8.

Yu, T., Tao, Y., Yang, M., Chen, P., Gao, X., Zhang, Y., Zhang, T., Chen, Z., Hou, J., Zhang, Y., et al. (2014). Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Research 24, 1214-1230.


成果转化节选

Method for detecting protein stability and uses thereof, Ronggui Hu, Tao Yu, Yonghui Tao, US20160068861A1.

Fungal cells and methods for production of very long chain fatty acid derived products, Florian David, Verena Siewers, Anastasia KRIVORUCHKO, Leonie WENNING, Tao Yu, Yong-jin ZHOU, Jens Nielsen, US20180112240A1.